GLP-1 is a hormone produced in the gut that influences insulin release and contributes to a reduction in appetite.Īnother 2022 study credits a combination berberine-cinnamon therapeutic with offering hepatoprotective effects. In a 2022 article published in Natural Products and Human Diseases, which is part of the “Advances in Experimental Medicine and Biology” book series, researchers indicate that cinnamon is one of several natural substances that helps modulate glucagon-like peptide-1 (GLP-1) expression and secretion. Though it is perhaps best known for adding flavor to tasty desserts such as cinnamon rolls, churros, and some cookies, research has also found that when combined with berberine, cinnamon offers more benefits for people with diabetes or prediabetes. This included having lower fasting blood glucose levels (HbA1c) and reductions in advanced glycation end products (AGEs) and malondialdehyde (MDA).Ĭinnamon is a spice that comes from the bark of trees in the Cinnamomum family. After taking a combination supplement for 12 weeks, individuals had significant glucose profile improvements.
They also had a reduction in their inflammatory status, reduced fasting and post-prandial glucose-plasma levels, and decreases in fasting plasma insulin.Ī 2021 study involving patients with type 2 diabetes also found positive blood sugar results. In a 2020 summary of the biological activities of berberine, researchers noted that previous studies have found that after taking a therapeutic with berberine and chromium picolinate, patients with fasting dysglycemia had improved cholesterol and triglyceride values. The human body only needs small amounts of chromium daily, with the adequate intake being between 20 and 35 micrograms per day according to the Office of Dietary Supplements, depending on age, sex, and whether a person is pregnant or lactating.
Berberine with chromium and cinnamonĬhromium is an essential mineral that plays a role in the metabolism of fats, carbs, and protein. Although each of these effects offers value on its own, combining berberine with chromium and cinnamon offers synergistic effects. Some of berberine’s benefits are related to its anti-inflammatory effects, while others are a result of this compound reducing oxidative stress, increasing cardiac output, and lowering lipid levels.
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